Microbial biological control agents have become the first choice to replace chemical pesticides due to their high efficiency, harmlessness to humans and animals, small pollution to the natural environment, and resistance.They are also a fast-developing and successfully applied biopesticide product. The biological safety of microbial control agents has certain risks. Toxicology and eco-toxicology tests are important test methods to evaluate the quality and safety of microbial biological control agents, and also important test to determine the safety classification of strains. Toxicological tests and eco-toxicological tests can form a complete safety assessment system and supervision and management means for the microbial fertilizer industry, so as to ensure the safety of producers, users and the environment. At the same time, it is of great significance for the establishment of risk warning and emergency response mechanism for the microbial biological control agents industry.
Toxicology and eco-toxicology are highly applicable tools in pollution prevention and control. The core part of toxicology is biological effect, that is, the study of the extent and scope of the harm of toxic and harmful substances to living organisms. Biomonitoring and bioassay are two technical means to study biological effects. Creative BioMart Microbe provides several strategies for accelerating the toxicological and eco-toxicological risk assessment process for microbial biological control agents.
We have established a series of strain identification platforms, including physiological, morphological, characteristic identification and functional evaluation. We can carry out different safety evaluation strategies according to different microbial control agent products, types and dosage forms.
We can test the technical indicators of the products, including effective viable bacteria number, miscellaneous bacteria rate, heavy metals, total nutrients, organic matter, physical and chemical indicators, etc.
According to the classification management list of strains, we determine the safety level of strains and the toxicological detection items that should be done. Acute oral toxicity tests are required for secondary strains, pathogenicity tests for tertiary strains, and median lethal dose (LD50) tests.
The effects of microbial biological control agents on soil organisms (microorganisms and animals) have become an important index for evaluating their ecological safety in many countries. By studying its acute toxicity, subacute toxicity, genetic toxicity and physiological toxicity to animals, we comprehensively analyzed the safety of microbial biological control agents.
Creative BioMart Microbe offers several technical services for the development of biological control agents, with personalized project solutions to realize different research needs. If you want to know more about this service, please feel free to contact us.
Reference:
Enter your email here to subscribe