Hormones are body's chemical messengers made by glands in the endocrine system. Hormonal communication, which relies on the production and release of hormones from various glands and on the transport of those hormones via the bloodstream, is responsible for a constant internal environment (i.e., homeostasis). In addition, hormones regulate many of the body's functions, including growth and development, metabolism, electrolyte balances, and reproduction.
The unbalance of hormones will lead to body problems including diabetes, weight gain or loss, infertility, weak bones. Moreover, the study found that some cancers, such as breast, endometrium, ovary, prostate, testis, thyroid, and osteosarcoma, are hormones sensitive or hormone dependent. The mechanism of hormones related cancers is that both endogenous and exogenous hormones increased the number of cell divisions and the opportunity for random genetic errors by driving cell proliferation.
Hormone therapy (or endocrine therapy) uses medicines to counteract deprivation, abnormal, and deleterious functions of endogenous hormones for stop or slow down the growth and development of cancer. Until now, hormone therapy has been successfully applied into the treatment of breast cancer, prostate cancer, endometrial cancer, and others. Therefore, hormones production plays an important role in the study of hormone function and hormone therapy in vitro.
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