Competitive Biological Antagonists Screening

The development of competitive biological antagonist products is one direction of the development of organic agriculture. The development of microbial biological control agents involves multistage screening of large numbers of antagonists in order to ensure that candidate antagonists are effective against specific pathogenic microorganisms. In order for the developed product to be suitable for commercial use, production costs, environmental risks, and safety of antagonist products to producers, users and plants, etc. are also considered. Creative BioMart Microbe provides customers with a service platform for competitive biological antagonist screening, helping customers to comprehensively evaluate antagonist candidates.

Competitive Biological Antagonist

Figure 1. Diffusible metabolite assay. (Chen, et al. 2018)

The use of competitive biological antagonists for the control of agricultural diseases exploits a common phenomenon among microorganisms. The competitive relationship between fungal/bacterial antagonists and phytopathogenic microorganisms makes this class of beneficial microorganisms potential antagonists. Competition for nutrients and space exists between antagonistic microorganisms and plant pathogens. Antagonist candidates can prevail in this competitive relationship, rapidly depleting the nutrients the pathogen needs, such as carbon and nitrogen sources, to resist infection by the pathogen. The fierce competition between antagonistic microorganisms and plant pathogens reduces the number of pathogens, thereby achieving the purpose of preventing or limiting the development of plant diseases caused by pathogenic microorganisms.

Competitive Biological Antagonists Screening Services

Creative BioMart Microbe provides comprehensive competitive biological antagonists screening solutions.

• Through the in vitro screening of antagonist candidates, researchers can evaluate the interaction between antagonists and pathogens, and analyze whether the antagonists are effective against the given pathogen.
• We provide technical services for the assay of diffusible metabolites and volatile compounds to assess whether antagonists produce diffusible metabolites or volatiles.
• The effectiveness of antagonists can also be assessed by testing the ability of antagonistic microorganisms to synthesize fungal cell wall degrading enzymes, so we also provide services to analyze the ability of candidates to produce and secrete hydrolases such as chitinases, proteases and cellulases.
• Our biofilm forming ability test service can also help you evaluate antagonistic microbial candidates more comprehensively.
• In vitro testing is required to assess the colonization activity of antagonistic microorganisms and to analyze the level of plant infection to select biologics with the best protection and colonization of roots, seeds, and seedlings.

Why Choose Creative BioMart Microbe?

• One-stop competitive biological antagonists screening solution, providing a number of technical services to help customers conduct a comprehensive analysis of competitive biological antagonists.
• The pathogen identification, isolation and purification services provided by our company can assist customers in their research.
• A team of many excellent biologists provides customers with satisfactory project solutions.
• Realize real-time technical communication and tracking services.

Workflow of Competitive Biological Antagonists Screening Service in Creative BioMart Microbe

If you want to know more information about this service, please feel free to contact us by phone or email, or you can consult through our inquiry form.

References

1. Khl, J., et al. Mode of action of microbial biological control agents against plant diseases: relevance beyond efficacy. Frontiers in Plant Science. 2019, 10: 845.
2. Chen, P. H., et al. Screening and evaluation of yeast antagonists for biological control of Botrytis cinerea on strawberry fruits. Mycobiology. 2018, 46(1): 33-46.