In the field of microbiology, in addition to microbial identification, sometimes our customers may need to distinguish and characterize microorganisms beyond the species level. Creative BioMart Microbe has established a strain typing platform that includes a variety of technical methods. Advanced technical methods and equipment, as well as experienced technical experts can help customers achieve rapid, efficient and reliable strain typing.
Strain Typing
The purpose of strain typing is to distinguish and classify different strains. Strain typing can identify the same strain in different samples, which helps to trace the source of microbial contamination. Different from microbial identification, strain typing can distinguish different strains of the same species and has a higher discrimination ability. Traditional strain typing methods include serological typing, phage typing and bacteriocin typing, etc. The strain typing methods such as MLST and WGS enable researchers to obtain faster and more sensitive strain typing results.
Strain Typing Service Can Benefit Our Customers in The Following Aspects:
- Tracing the source of food poisoning
- Conduct research in the field of epidemiology and establish a connection between individual cases and outbreaks of infectious diseases
- Study the function of individual strains in the human microbiome
- Investigate the root causes of microbial contamination in the industry, such as the investigation of microbial contamination in sterile preparations
- Characterize microorganisms with critical applications
Our Strain Typing Technology Platforms
Creative BioMart Microbe has established a variety of technology platforms that can be used for strain typing. You can choose according to your needs, or decide through in-depth communication with our technical experts on the project. The scientific and meticulous research program will guarantee high-quality experimental results.
- MultiLocus Sequence Typing (MLST)
MLST amplifies seven housekeeping genes internal fragments by PCR, and uses sequence determination to perform strain typing. MLST is a genotyping technology with high resolution capabilities that can detect small differences within microbial species. We have established an accurate MLST typing system, which can provide support for epidemiological studies.
- Pulsed-Field Gel Electrophoresis (PFGE)
PFGE is a molecular typing technique widely used in epidemiological research, which uses the different migration of macro-restriction fragments in different strains to distinguish them. We can provide customers with fast, reliable and highly reproducible strain typing results based on the PFGE platform.
- Ribotyping
Ribotyping technology uses the stability of ribosomal RNA genes for strain typing. Creative BioMart Microbe provides automated ribotyping services, which can provide customers with reliable and reproducible strain typing results within a short experimental period.
- Repetitive Element Palindromic PCR (Rep-PCR)
Different maps can be obtained through amplifying the repetitive sequences of bacterial genomic DNA. Rep-PCR is a general microbial typing method with strong distinguishing ability. Through our rep-PCR technology platform, we provide a one-stop service from DNA extraction and primer design to data analysis to ensure fast and reproducible experimental results.
- Whole Genome Sequencing (WGS)
Creative BioMart Microbe also provides the WGS technology platform for strain typing. The WGS technology platform can realize genome sequencing and polymorphism analysis of bacterial isolates. Our bioinformatics experts can also analyze the genetic correlation information of bacterial isolates to help customers conduct related research in epidemiology and other fields.
Workflow of Strain Typing Services
If you want to know more about the strain typing service, please contact us by phone or email, or contact us through our inquiry form.
Related Services:
