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Drug and Active Molecule Discovery

Drug discovery is a long and arduous process that can eventually bring molecules from the laboratories to the market. In generally, only 1 molecule out of 5000 hit candidates can reach the market successfully. It is important for pharmaceutical companies to optimize the drug and active molecule discovery process.

Drug and Active Molecule DiscoveryFigure 1. Drug discovery process with decision-making tools and key decision points. (Eric, et al. 2011)

As a professional biopharmaceutical microbiology company, Creative BioMart Microbe is your best choice of partner to accelerate program. We offer different approaches in drug and active molecule discovery.

Genome Analysis

The Human Genome Project and related efforts have led to an unprecedented proliferation of both public and private databases of genomic data, which opens the door to use of molecular profiling for every step in the drug and active molecule discovery and development process.

High-Throughput Screening (HTS)

HTS is drug discovery process running millions of biological or chemical tests in a short time. Based on modern advances in robotics, liquid handling, plate reader detection and computers, HTS can obtain target candidates more efficiently.

Microbial Extracts Screening

Microbial extracts yielded by bacterial, fungal, plant, and marine sources, represent a large family of diverse chemical entities with a wide variety of biological activities. Microbial extracts serve as a valuable source for novel molecular scaffolds in drug development, and around 65% of all approved drugs are classified as natural products or are inspired by a natural products core.

Why Choose Creative BioMart Microbe?

  • Advanced bioinformatic tools and genome mining approaches.
  • Skilled team and equipped laboratories.
  • Reliable experimental design and complete record.
  • Short turnaround time and competitive price.

Creative BioMart Microbe is aiming to offers comprehensive and custom services to our clients, please feel free to contact us for more information.

References:

  1. Paytubi, S.; et al. A High-Throughput Screening Platform of Microbial Natural Products for the Discovery of Molecules with Antibiofilm Properties against Salmonella. Frontiers in Microbiology. 2017, 8.
  2. Eric, C., Jean-Robert, I. Drug discovery and development for neglected diseases: the DNDi model. Drug Design, Development and Therapy. 2011, 175.
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