Yeast is an excellent host to produce functional recombinant proteins. The potential for secretory expression of heterologous proteins in yeast indicates that this system can be a candidate for the production of complex eukaryotic proteins. For the production of each specific product, the most suitable expression system should be selected and optimized both on the genetic and fermentation level, and at the same time the characteristics of the host, vector, and expression strategy should be considered. The current common practice is to select the most similar to the mammalian system and stable production yeast strains to produce recombinant proteins in yeast with high yield and high quality.
The famous Saccharomyces cerevisiae expression system was used as the major expression host in the 1980s, and it plays an important role in brewing, baking, and wine making. In addition, the development of Saccharomyces cerevisiae genome sequencing also provides valuable information on many aspects of genome organization and evolution. In industrial ethanol production, Saccharomyces cerevisiae is a better host than bacteria and other yeasts because Saccharomyces cerevisiae has tolerance to a wide pH range, high concentration of sugar and ethanol, and resistance to high osmotic pressure. In addition to industrial production, the expression system is often used to study gene expression regulation, signal transduction, apoptosis, cell cycle control, neurodegenerative diseases, autophagy, and many other important biological procedures. This system is generally regarded as safe (GRAS) because Saccharomyces cerevisiae is non-pathogenic and has been used in various biopharmaceutical production and nutritional industries.
Creative BioMart Microbe is an expert in yeast protein expression and production, and has accumulated nearly 20 years of experience in this field. In addition to our excellent bacterial protein expression system, we also provide cheap, easy-to-operate, stable, and mature yeast protein expression systems, including Pichia pastoris and Saccharomyces cerevisiae. Our Saccharomyces cerevisiae protein expression system can not only help customers produce large-scale active recombinant proteins, but also help customers study many other physiological processes. At present, the system has been optimized and upgraded to overcome weaknesses such as high glycosylation of protein, low protein yield and plasmid instability. At present, the expression and production of numerous target proteins have been completed.
Creative BioMart Microbe is a biotechnology company with many years of experience in protein expression and purification. The advanced technology platform we have established is jointly managed by professional biochemical experts and protein experts. Our professional knowledge and perfect after-sales service have made us a trusted service provider for many customers.
If you want to know more about this service, please feel free to contact us by phone or email, or you can consult through our inquiry form. We will ensure to provide you with efficient and high-quality experimental outsourcing services.
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