Fermentation Process Development & Optimization Services
Fermentation technology is widely used to produce a variety of economically important compounds that have been used in the energy production, pharmaceutical, chemical and food industries. Although fermentation processes are handed down from generation to generation, there is a challenging need for sustainable production of products that meet market demand in an economical and efficient manner.
At present, there are some problems in the production process of fermentation industry, such as extensive production, poor product quality, high consumption of resources and energy, and serious environmental pollution.
Figure 1. Schematic diagram of a systematic approach of fermentation medium designing.
Creative BioMart Microbe’s fermentation production laboratory mainly carry out metabolite production, fermentation, development and optimization services through the following points (including but not limited to other conventional techniques relating to fermentation):
- Identification/design of fermentation strains to match industrial fermentation strains or relevant fermentation strains for vaccine production
- Systematic method and optimization of fermentation medium design
- Analysis and optimization of fermentation conditions
- Nutritional control of metabolites
- Optimization of fermentation kinetics
- Expansion of culture stage
Creative BioMart Microbe centered on the key technology of the fermentation process optimization and control, in order to obtain high yield, high substrate conversion rate and high production strength relatively unified as the goal, from optimization of microbial genes, regulating intracellular microenvironment and optimize the macro environment, the development of the comprehensive consideration biology, kinetics and physics phenomenon of the fermentation process optimization technology to meet the market demand and research needs.
Why Choose Creative BioMart Microbe? What Do We Have About Our Fermentation Platform?
Full Staffing
- We have researchers from the field of fermentation engineering and microbiology, who can develop and optimize the whole fermentation process
- Have operators engaged in fermentation industry for many years, familiar with the operation of fermentation tank and various analytical equipment
- Have a professional QC team, able to complete APQP/PPAP and other documents and technical documentation
High Quality Fermentation Equipment
- Large scale fermenter, pilot scale fermenter and experimental fermenters
- Hollow fiber filtration system
- Frozen centrifuge
A Variety of Expression Systems
We have a variety of expression systems, including E. coli expression system, Bacillus subtilis expression system, Pichia pastoris expression system, Saccharomyces cerevisiae expression system, etc.
Optimized Processes Provided by Creative BioMart Microbe
Figure 2. The Scheme roughly illustrating the theoretical steps and stages of fermentation process optimization and scale up.
Creative BioMart Microbe can undertake the development of technology such as strain screening and process amplification and optimization. If you want to know more test information and price information, please feel free to contact us and we will reply to you as soon as possible.
Reference
- Singh, V.; et al. Strategies for fermentation medium optimization: an in-depth review. Frontiers in Microbiology. 2016, 7: 2087.
