Cat.No.
p17-247
Species
Treponema pallidum
Product Name
Recombinant Treponema pallidum p17 protein
Product Overview
Recombinant Treponema pallidum p17 containing beta-galactosidase (114 kDa) fused at the N-terminus and T. Pallidum p17 immunodominant regions was expressed in E. coli
Description
Treponema pallidum is a gram-negative spirochaete bacterium and is considered to be metabolically crippled. There are at least four known subspecies: T. pallidum pallidum, T. pallidum pertenue, T. pallidum carateum and T. pallidum endemicum. The helical structure of T. pallidum pallidum allows it to move in a corkscrew motion through viscous mediums such as mucus. Treponema pallidum sub sp. pallidum has one of the smallest bacterial genomes at 1.14 million base pairs (Mb) and has limited metabolic capabilities, reflecting its adaptation through genome reduction to the rich environment of mammalian tissue.
Source
E. coli
Form
8M urea, 20mM Tris-HCl pH-8 and10mM B-ME.
Bio-activity
Immunoreactive with sera of Trp. Pallidum infected individuals.
Purity
Treponema Pallidum protein protein is >90% pure as determined by 10% PAGE (coomassie staining).
Applications
Treponema Pallidum protein is suitable for ELISA and Western blots, excellent antigen for detection of Trp. Pallidum with minimal specificity problems.
Storage
Treponema Pallidum protein although stable at 4°C for 1 week, should be stored below -18°C.Please prevent freeze thaw cycles.
