Cat.No.
CDA067P
Species
Mycobacterium Tuberculosis
Product Name
Recombinant Mycobacterium Tuberculosis major secretory protein Antigen 85B
Product Overview
Recombinant Ag85B His-Tag fusion protein produced in E.Coli is a single, non-glycosylated polypeptide chain having a molecular mass of 30 kDa.
Description
Antigen 85B Mycobacterium Tuberculosis- is the most abundant protein exposed by M. Tuberculosis, as well as a potent immunoprotective antigen and a leading drug target. Ag85 induces strong T-cell proliferation and IFN-g secretion in most healthy individuals exposed to M. tuberculosis, in BCG-vaccinated mice and humans, whereas the antibody against Ag85 are more prevalent in active tuberculosis patients with decreased cellular immune response.
Source
E. coli
Form
The protein was lyophilized with no additives.
Purity
Greater than 90.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Storage
Ag85B although stable room temperature for 4 weeks, should be stored desiccated below -18℃. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Synonyms
Antigen 85B; Mycobacterium Tuberculosis major secretory protein Antigen 85B.
