Cat.No.
pxo1_110-01B
Species
Bacillus anthracis
Product Name
Recombinant Bacillus anthracis pxo1_110 Protein
Product Overview
Recombinant Bacillus anthracis pxo1_110 (PA) Protein 30-764aa (signal peptide removed), fused with no tag, was expressed in Bacillus.
Description
One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax.
Source
Bacillus
Predicted N Terminal
Glu 30
Form
Lyophilized from sterile PBS, pH 7.4.
Bio-activity
Measured by its binding ability in a functional ELISA.
Molecular Mass
The recombinant mature bacillus anthrax protein antigen consists of 735 amino acids and has a calculated molecular mass of 82.7 KD.
Endotoxin
<1.0EU/ug, LAL method
Purity
>95% (SDS-PAGE)
Stability
Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage
Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Official Symbol
pxo1_110
