Cat.No.
Streptolysin-171S
Species
Streptococcus hemolyticus
Product Name
Native Streptolysin O protein
Description
Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation.
Source
Purified from Streptococcus hemolyticus
Form
Liquid
Protein length
Full length native Streptolysin O
Purity
>95% (SDS-PAGE)
Applications
Western blotting,ELISA,etc.
Storage
Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage Buffer
PBS
